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How to cross/break an azeotrope?

Discussion in 'Qualification & Validation (Also 21 CFR Part 11)' started by Bates74, Sep 13, 2021.

  1. Bates74

    Bates74 New Member

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    A pressure-sensitive azeotrope can be shifted/moved in a single volume without adding any entrainer. By adding an inert gas (e.g. nitrogen), the dew pressure of condensable vapours within said single volume can be varied, while keeping the total pressure constant.
     
  2. Andy Nichols

    Andy Nichols Moderator Staff Member

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    Is this a question or guidance in the context of 21 CFR Part 11?